Weight Loss · Muscle Performance · Seattle

Lose the fat. Keep the muscle.

Up to 25–40% of weight lost on GLP-1 medication without resistance training and adequate protein can be lean mass. Muscle is the organ of longevity — this program is built to protect it while the scale moves.

What is medically supervised weight loss with Dr. Simon? A physician-managed program at Rebel Med NW in Seattle combining GLP-1 receptor agonist therapy (semaglutide, tirzepatide) when appropriate, cardio-metabolic and hormone evaluation, body composition (BIA) tracking, protein-forward nutrition planning, and resistance-training programming from a physician with a BS in Exercise Science. Body-positive, mechanism-first, and honest about evidence.
The Problem

Weight loss done wrong ages you.

Adults lose roughly 0.8% of muscle mass per year from age 30 — faster after 60. Crash diets and unsupported GLP-1 prescriptions accelerate that loss. Lower muscle mass predicts higher mortality, worse blood sugar control, more falls, and less independence later in life.

The goal was never a smaller number. It's a better body composition: less visceral fat, preserved lean mass, stronger metabolic machinery.

The Program

What your plan includes.

  • Medical evaluation — cardio-metabolic, endocrine, and hormone labs where indicated; medication history and safety screening
  • GLP-1 therapy when appropriate — compounded semaglutide from $200/mo, tirzepatide from $325/mo, with physician monitoring
  • Body composition tracking — BIA analysis of lean mass, body fat, hydration, and BMR ($49.99 intro test; included in GLP-1 programs)
  • Muscle-first programming — resistance training targets and protein planning (typically 1.6–2.2 g/kg/day)
  • Behavioral coaching — mind-body medicine and motivational support so changes hold
  • All-inclusive memberships — from $150/month
The Evidence

Numbers worth knowing.

~15%average body-weight reduction with semaglutide 2.4 mg over 68 weeks (STEP 1, NEJM 2021)
25–40%of GLP-1 weight loss can be lean mass without resistance training and adequate protein
0.8%/yrtypical muscle loss from age 30 — the baseline you're defending
2×/weekresistance training sessions shown to preserve lean mass during weight loss

GLP-1 medications are prescription therapies with real contraindications and side effects. This page is educational; medication decisions happen in a medical visit after evaluation.

Watch · In the Community

Stress, weight, and the nervous system.

Watch — Dr. Simon's KING 5 interview on stress & pandemic weight gain

Weight change is rarely just calories. Cortisol, sleep, and nervous-system load shape appetite, cravings, and where the body stores fat — which is why this program treats stress physiology as seriously as nutrition and training.

Dr. Andrew Simon with staff after a body-composition presentation at a local Seattle gym
Teaching body-composition basics at a local Seattle gym
FAQ

Weight loss questions.

Do I have to take medication to join the program?

No. Many patients run nutrition, training, and metabolic treatment without GLP-1 therapy. Medication is one tool — used when evaluation supports it and skipped when it doesn't.

Is GLP-1 therapy covered by insurance?

Coverage for weight loss indications is inconsistent. Visits may be billable when tied to conditions like diabetes, hypertension, or hyperlipidemia. Direct pricing is transparent: compounded semaglutide from $200/month, tirzepatide from $325/month.

How do you protect muscle during weight loss?

Protein targets around 1.6–2.2 g/kg/day, progressive resistance training at least twice weekly, adequate sleep, dose titration that respects appetite suppression, and BIA re-testing so lean mass loss is caught early — not discovered at the end.

What happens when I stop GLP-1 medication?

Without habit and muscle infrastructure, weight regain is common — about two-thirds of lost weight regained within a year of stopping in the STEP 1 extension study. That's why this program builds training, protein, and behavior first, so the medication is a phase, not a dependency.

Next Step

Start with a body composition baseline.

BIA analysis + 15-minute physician consult — $49.99 introductory offer.

Book It